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A Comprehensive Understanding of Choroidal Metastasis from Lung Cancer
OncoTargets and Therapy ( IF 4 ) Pub Date : 2021-08-12 , DOI: 10.2147/ott.s315532
Zihan Qu 1 , Jiewei Liu 1 , Lingling Zhu 1 , Qinghua Zhou 1
Affiliation  

Abstract: The incidence of lung cancer with intraocular metastasis is low, of which choroidal metastasis is the most painful metastatic lesion. The clinical symptoms resulting from choroidal metastasis from lung cancer easily detected although they are rarely identified prior to the diagnosis of the primary malignancy. The quality of life of patients is inevitably impaired. Some lung cancer patients complain of ocular symptoms as the first manifestation of lung cancer. Early diagnosis and treatment can significantly overcome or delay the visual impairment and improve prognosis. The main therapeutic modalities include systemic and local treatments, while observation is also a treatment option. Currently, the feasibility and effectiveness of various treatment options are controversial worldwide. Herein, we summarize the underlying mechanisms, epidemiology, clinical features, auxiliary examinations, diagnosis, and recent treatment options for intraocular metastases.

Keywords: intraocular tumor, cancer therapeutics, systemic therapy, local therapy


中文翻译:

全面了解肺癌脉络膜转移

摘要:肺癌眼内转移的发生率较低,其中脉络膜转移是最痛苦的转移病灶。肺癌脉络膜转移引起的临床症状很容易检测到,尽管它们很少在原发恶性肿瘤诊断之前被发现。患者的生活质量不可避免地受到损害。一些肺癌患者抱怨眼部症状是肺癌的首发表现。早期诊断和治疗可以显着克服或延缓视力障碍,改善预后。主要治疗方式包括全身治疗和局部治疗,观察也是一种治疗选择。目前,各种治疗方案的可行性和有效性在世界范围内都存在争议。在此,我们总结了潜在的机制、流行病学、

关键词:眼内肿瘤,癌症治疗,全身治疗,局部治疗
更新日期:2021-08-11
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