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Effects of two different acute and subchronic stressors on gastrointestinal transit in the rat: A radiographic analysis
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2021-08-11 , DOI: 10.1111/nmo.14232
Ana Bagues 1, 2, 3 , Yolanda Lopez-Tofiño 1, 4 , Carlos Galvez-Robleño 1, 4 , Raquel Abalo 1, 3, 4, 5
Affiliation  

The reaction to stress is an adaptive response necessary for survival. When stressors are repeated, the organism adapts, although these adaptive responses can become dysregulated and result in disease, causing gastrointestinal (GI) disorders. Radiographic methods allow the non-invasive study of how a given factor affects GI transit in the same animal at different time points. These methods have never been applied to study the consequences of stress on GI motor function and their dependency on time and stimulus. Therefore, our aim was to characterize, using radiographic techniques, the effect on GI transit of cold-restraint (CR) and forced swim (FS) stress applied acutely and subchronically in the rat.

中文翻译:

两种不同的急性和亚慢性应激源对大鼠胃肠道转运的影响:放射学分析

对压力的反应是生存所必需的适应性反应。当压力源重复出现时,有机体会适应,尽管这些适应反应可能会变得失调并导致疾病,从而导致胃肠道 (GI) 疾病。射线照相方法允许对给定因素如何影响同一动物在不同时间点的胃肠道运输进行非侵入性研究。这些方法从未用于研究压力对胃肠道运动功能的影响及其对时间和刺激的依赖性。因此,我们的目标是使用放射照相技术来表征在大鼠中急性和亚慢性施加的冷约束 (CR) 和强迫游泳 (FS) 应激对 GI 转运的影响。
更新日期:2021-08-11
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