Ambulatory blood pressure (BP) monitoring (ABPM) may cause sleep disturbances. Some home BP monitoring (HBPM) devices obtain a limited number of BP readings during sleep and may be preferred to ABPM. It is unclear how closely a few BP readings approximate a full night of ABPM. We used data from the Jackson Heart (N = 621) and Coronary Artery Risk Development in Young Adults (N = 458) studies to evaluate 74 sampling approaches to estimate BP during sleep. We sampled two to four BP measurements at specific times from a full night of ABPM and computed chance-corrected agreement (i.e., kappa) of nocturnal hypertension (i.e., mean asleep systolic BP ≥ 120 mmHg or diastolic BP ≥ 70 mmHg) defined using the full night of ABPM and subsets of BP readings. Measuring BP at 2, 3, and 4 h after falling asleep, an approach applied by some HBPM devices obtained a kappa of 0.81 (95% confidence interval [CI]: 0.78, 0.85). The highest kappa was obtained by measuring BP at 1, 2, 4, and 5 h after falling asleep: 0.84 (95% CI: 0.81, 0.87). In conclusion, measuring BP three or four times during sleep may have high agreement with nocturnal hypertension status based on a full night of ABPM.

动态血压 (BP) 监测 (ABPM) 可能会导致睡眠障碍。一些家庭血压监测 (HBPM) 设备在睡眠期间获取数量有限的血压读数，可能优于 ABPM。目前尚不清楚一些 BP 读数与一整夜的 ABPM 有多接近。我们使用了杰克逊心脏 ( N  = 621) 和年轻人冠状动脉风险发展 ( N = 458) 研究评估 74 种抽样方法来估计睡眠期间的血压。我们在特定时间从一整夜的 ABPM 中抽取了两到四次 BP 测量值，并计算了使用整晚的 ABPM 和 BP 读数的子集。在入睡后 2、3 和 4 小时测量血压，一些 HBPM 设备应用的方法获得了 0.81 的 kappa（95% 置信区间 [CI]：0.78，0.85）。通过在入睡后 1、2、4 和 5 小时测量血压获得最高 kappa：0.84（95% CI：0.81、0.87）。总之，在睡眠期间测量 3 次或 4 次血压可能与基于整晚 ABPM 的夜间高血压状态高度一致。