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Plasmacytoid dendritic cells-derived IFN-α is involved in Helicobacter pylori infection-induced differentiation of Schlafen 4–expressing myeloid-derived suppressor cells
Infection and Immunity ( IF 3.1 ) Pub Date : 2021-08-02 , DOI: 10.1128/iai.00407-21
Xiaodan Xiang 1 , Yaping Wu 1 , Hongwei Li 1 , Cun Li 1 , Lu Yan 1 , Qian Li 1
Affiliation  

During chronic infection with Helicobacter pylori, Schlafen 4-expressing myeloid-derived suppressor cells (SLFN4+ MDSCs) create a microenvironment favoring intestinal metaplasia and neoplastic transformation. SLFN4 can be induced by IFN-α, which is mainly ...

中文翻译:

浆细胞样树突状细胞衍生的 IFN-α 参与幽门螺杆菌感染诱导的 Schlafen 4 表达髓源性抑制细胞分化

在幽门螺杆菌慢性感染期间,表达 Schlafen 4 的髓源性抑制细胞 (SLFN4+ MDSC) 创造了有利于肠化生和肿瘤转化的微环境。SLFN4可由IFN-α诱导,主要是...
更新日期:2021-09-12
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