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Dynapenic abdominal obesity in hospitalized elderly patients with acute myocardial infarction
Experimental Gerontology ( IF 3.9 ) Pub Date : 2021-08-10 , DOI: 10.1016/j.exger.2021.111512
Clécia Alves da Silva 1 , Roberta Maria Lins Mendes 2 , Natália de Moraes Santana 2 , Natalia Fernandes Dos Santos 2 , Cláudia Porto Sabino Pinho 3
Affiliation  

Obesity and dynapenia are cardiovascular risk factors. When present together, it is called dynapenic abdominal obesity and can potentiate adverse outcomes. This study aims to estimate the prevalence of dynapenic abdominal obesity and its relationship with prognostic markers in patients with acute myocardial infarction (AMI). This is a hybrid study with a longitudinal component plus a cross-sectional component at baseline involving elderly patients admitted to a reference hospital in cardiology due to AMI in the Brazilian Northeast from May to October 2015. We analyzed patients' admission data and evaluated some prognostic markers up to two years after admission. We established abdominal obesity by measuring waist circumference (>102 cm for men and >88 cm for women) and dynapenia by handgrip strength (<27 kg/F for men and <16 kg/F for women). We considered the prognostic markers troponin and creatinine kinase - MB (CKMB), AMI classification according to ST segment elevation, TIMI score, need for coronary angioplasty or coronary artery bypass surgery, complications during hospitalization and within two years after admission, and re-admission to the same service. We evaluated 92 patients with a mean age of 71.4 ± 7.5 years. The prevalence of abdominal obesity and dynapenia was 56.5% and 44.6%, respectively. The coexistence of the two conditions occurred in 25.0% of the patients, being higher among women (p < 0.001). When comparing the dynapenic abdominal obese groups with the group of patients who had one of the two isolated conditions we observed that, for a same mean age and clinical characteristics, patients with only one of the conditions had a higher CKMB (p = 0.046) and troponin median (p = 0.032). The presence of dynapenia in the groups of abdominal obese and non-abdominal obese individuals is not associated with risk marker parameters (p > 0.05). High prevalence of abdominal obesity and dynapenia occurred among patients with AMI and in a quarter of these both conditions coexisted. Dynapenic abdominal obesitydoes not increase the risk of adverse outcomes and isolated dynapenia is not a marker of a poor prognosis.



中文翻译:

老年急性心肌梗死住院患者的动态腹型肥胖

肥胖和肌无力是心血管危险因素。当一起出现时,它被称为动力性腹部肥胖,并可能加剧不良后果。本研究旨在评估急性心肌梗塞 (AMI) 患者中动力性腹部肥胖的患病率及其与预后标志物的关系。这是一项包含纵向成分和基线横断面成分的混合研究,研究对象为 2015 年 5 月至 10 月在巴西东北部因 AMI 入住心脏病参考医院的老年患者。我们分析了患者的入院数据并评估了一些预后入学后最多两年的标记。我们通过测量腰围(男性 > 102 厘米,女性 > 88 厘米)和握力(男性 < 27 kg/F 和 < 女性 16 公斤/华氏度)。我们考虑了预后标志物肌钙蛋白和肌酐激酶 - MB (CKMB)、根据 ST 段抬高的 AMI 分类、TIMI 评分、冠状动脉成形术或冠状动脉搭桥手术的需要、住院期间和入院后两年内的并发症以及再次入院到相同的服务。我们评估了 92 名平均年龄为 71.4 ± 7.5 岁的患者。腹部肥胖和肌无力的患病率分别为 56.5% 和 44.6%。25.0% 的患者同时存在这两种情况,女性更高(p < 0.001)。当将有动力的腹部肥胖组与具有两种孤立病症之一的患者组进行比较时,我们观察到,对于相同的平均年龄和临床特征,仅患有其中一种病症的患者具有较高的 CKMB(p = 0.046)和肌钙蛋白中位数(p = 0.032)。腹部肥胖和非腹部肥胖个体组中出现的肌无力与风险标记参数无关(p > 0.05)。AMI 患者腹部肥胖和肌无力的患病率很高,其中四分之一的患者同时存在这两种情况。Dynapenic 腹部肥胖不会增加不良结果的风险,孤立的 dynapenia 不是预后不良的标志。AMI 患者腹部肥胖和肌无力的患病率很高,其中四分之一的患者同时存在这两种情况。Dynapenic 腹部肥胖不会增加不良结果的风险,孤立的 dynapenia 不是预后不良的标志。AMI 患者腹部肥胖和肌无力的患病率很高,其中四分之一的患者同时存在这两种情况。Dynapenic 腹部肥胖不会增加不良结果的风险,孤立的 dynapenia 不是预后不良的标志。

更新日期:2021-08-23
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