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Pickering emulsions stabilized by biocompatible particles: A review of preparation, bioapplication, and perspective
Particuology ( IF 3.5 ) Pub Date : 2021-08-10 , DOI: 10.1016/j.partic.2021.07.003
Tong Zhang 1 , Fuguo Liu 1, 2 , Jie Wu 3 , To Ngai 1
Affiliation  

The phenomenon of adsorption of solid particles at fluid interfaces to stabilize emulsions or foams have been known for more than a century. Today, particle-stabilized emulsions, often referred to as Pickering emulsions, are receiving growing attention as they are encountered in oil recovery and have long been used in personal care products and food industry. In the past 10 years the focus of the Pickering emulsion has also increasingly shifted to biomedical applications with thanks to novel syntheses of a wide range of biocompatible particle stabilizers. Here, a brief overview of the development of biocompatible particles is given for Pickering emulsion stabilization, including alginate, poly(lactic-co-glycolic acid) (PLGA), and protein-based particles. The materials capable of being prepared by templating from emulsion stabilized with biocompatible particles include colloidal capsules and hierarchically porous materials. It is hoped that the understanding gained from the recent intense activity in the field will enable more researchers to modify existing materials and design new formulations, which would be beneficial for exploring more biological applications.



中文翻译:

生物相容性颗粒稳定的 Pickering 乳液:制备、生物应用和前景的综述

在流体界面吸附固体颗粒以稳定乳液或泡沫的现象已经为人所知一个多世纪了。今天,颗粒稳定的乳液,通常被称为 Pickering 乳液,由于它们在采油中遇到并且长期用于个人护理产品和食品工业,因此受到越来越多的关注。在过去的 10 年中,由于各种生物相容性颗粒稳定剂的新型合成,Pickering 乳液的重点也越来越多地转向生物医学应用。在这里,简要概述了用于 Pickering 乳液稳定的生物相容性颗粒的开发,包括海藻酸盐、聚(乳酸-共聚)乙醇酸)(PLGA)和基于蛋白质的颗粒。能够从用生物相容性颗粒稳定的乳液模板制备的材料包括胶体胶囊和分级多孔材料。希望从该领域最近的激烈活动中获得的理解将使更多的研究人员能够修改现有材料并设计新的配方,这将有利于探索更多的生物应用。

更新日期:2021-08-10
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