Associated with a significant morbidity and mortality, neurocandidiasis affects severely immunocompromised patients, especially if recently treated with antibiotics or corticosteroids. We present the case of a 70-year-old man admitted to an intensive care unit due to a Sars-Cov-2 pneumonia, with fever, coma, and multifocal neurological deficits reported 13 days after extubation. After isolation of Candida albicans in both urine and blood cultures and a brain MRI with multiple gadolinium-enhanced ring lesions, a diagnosis of neurocandidiasis was assumed and aggressive antifungal therapy started. During treatment, the patient developed a hospital-acquired pneumonia with fatal outcome.

与显着的发病率和死亡率相关，神经念珠菌病会影响严重免疫功能低下的患者，尤其是最近接受抗生素或皮质类固醇治疗的患者。我们介绍了一名 70 岁男性因 Sars-Cov-2 肺炎入住重症监护病房的病例，在拔管后 13 天报告发烧、昏迷和多灶性神经功能缺损。在尿液和血培养中分离出白色念珠菌并进行多处钆增强环状病变的脑部 MRI 后，假设诊断为神经念珠菌病，并开始积极的抗真菌治疗。在治疗过程中，患者患上了医院获得性肺炎，结果是致命的。