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Gold nanoparticles: Synthesis properties and applications
Journal of King Saud University-Science ( IF 3.8 ) Pub Date : 2021-08-10 , DOI: 10.1016/j.jksus.2021.101560
Inès Hammami 1 , Nadiyah M. Alabdallah 1 , Amjad Al jomaa 1 , Madiha kamoun 2
Affiliation  

In recent years, nanotechnology has been the topic of extensive research and a great deal of interest among researchers. The manufacturing and utilization of nanoparticles (NPs) has expanded dramatically as a result of the rapid development of nanotechnology. Gold nanoparticles (AuNPs) are one of the most important nanoparticles, and they have been widely used for medical and non-medical applications as ideal material because of their unique distinct features: inert, biocompatible, and especially due to low toxicity. It is can be manufacture on a massive scale by reducing the oxidation of gold Au+1(aureus) or Au+3(auric) to Au0 by subjoin a reducing agent through various physical, chemical, and biological methods under different circumstance. Researchers have been motivated by the harmful effects of current synthesis methods to focus on the production of environmentally sustainable and green synthesis using non-toxic chemicals from natural sources, such as plant extract, bacteria, and fungi. The preparation of Gold nanoparticles can be done inwardly or outside by microbes, but outside the cell handling is facile in terms of insulation. Modified nanocellulose is a preferred technique for gold nanoparticle extraction. AuNPs have shown outstanding applications for diagnostic and therapeutic uses, including biosensor applications, tumor-targeting capability (Anticancer Activity) for cancer therapy, and precise drug delivery of nano-vehicles to diseased tissues.



中文翻译:

金纳米粒子:合成特性和应用

近年来,纳米技术已成为广泛研究的主题,并引起了研究人员的极大兴趣。由于纳米技术的快速发展,纳米颗粒 (NPs) 的制造和利用急剧扩大。金纳米粒子 (AuNPs) 是最重要的纳米粒子之一,由于其独特的独特特性:惰性、生物相容性,尤其是低毒性,它们作为理想材料被广泛用于医疗和非医疗应用。它可以通过将金 Au +1(金黄色)或 Au +3(金)的氧化还原为 Au 0来大规模制造在不同情况下通过各种物理、化学和生物方法将还原剂再加入。当前合成方法的有害影响促使研究人员专注于使用来自天然来源(如植物提取物、细菌和真菌)的无毒化学品进行环境可持续和绿色合成。金纳米粒子的制备可以在内部或外部由微生物完成,但在绝缘方面,细胞外的处理很容易。改性纳米纤维素是金纳米颗粒提取的首选技术。金纳米粒子在诊断和治疗方面表现出出色的应用,包括生物传感器应用、癌症治疗的肿瘤靶向能力(抗癌活性),以及纳米载体向患病组织的精确药物递送。

更新日期:2021-08-17
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