This case report details the efficacy of in-clinic customized scleral lens trial with self-preserved antibiotic eye drop in the liquid reservoir, in promoting fast healing of persistent corneal epithelial defect (PED). A 57-year-old man with a PED following injury, not responding to conventional treatment, underwent an in-clinic therapeutic trial of prosthetic replacement of ocular surface ecosystem device, to promote epithelial healing. After device wear with antibiotic eye drop in the liquid reservoir for 8 hrs during the day on five consecutive days and pressure patching at night with antibiotic eye ointment, there was complete resolution of the PED. Prosthetic replacement of ocular surface ecosystem scleral lenses are an effective treatment modality for PED. In-clinic daytime lens wear with night time pressure patching is a cost-effective option. Expert supervision avoids patient learning curve issues. Corneal re-epithelization happens because of the moisture and protection of the fragile healing epithelium afforded by these high DK lenses.

中文翻译：

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眼表生态系统巩膜镜片的假体更换：持续性角膜上皮缺陷的临床治疗方法的好处。

本病例报告详细介绍了临床定制巩膜镜片试验在液体储存器中使用自保存抗生素滴眼液促进持续性角膜上皮缺损 (PED) 快速愈合的功效。一名受伤后患有 PED 的 57 岁男性对常规治疗无反应，接受了眼表生态系统装置假体置换的临床治疗试验，以促进上皮愈合。连续 5 天白天在储液器中佩戴抗生素眼药水 8 小时，晚上用抗生素眼膏加压修补后，PED 完全消退。眼表生态系统巩膜镜片的假体更换是 PED 的有效治疗方式。带夜间压力修补的诊所白天配戴镜片是一种经济高效的选择。专家监督避免了患者学习曲线问题。由于这些高 DK 镜片提供的脆弱愈合上皮的水分和保护，角膜上皮再生的发生。