Association of peripapillary hyper-reflective ovoid masslike structures and disease duration in primary progressive multiple sclerosis,European Journal of Neurology

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Association of peripapillary hyper-reflective ovoid masslike structures and disease duration in primary progressive multiple sclerosis
European Journal of Neurology ( IF 5.1 ) Pub Date : 2021-08-09 , DOI: 10.1111/ene.15056
Rebecca Wicklein _{1,

2} , Josephine Wauschkuhn ₁ , Katrin Giglhuber ₁ , Tania Kümpfel _{2,

3} , Bernhard Hemmer _{1,

2,

4} , Joachim Havla _{2,

3} , Benjamin Knier _{1,

2}

Affiliation

Peripapillary hyper-reflective ovoid masslike structures (PHOMS) are a novel finding during retinal optical coherence tomography in patients with multiple sclerosis (MS). To date, there are no data on the occurrence of PHOMS in early MS. The aim of this study was to investigate the frequency of PHOMS in patients with first diagnosed early relapsing–remitting MS (RRMS) and to search for associations of PHOMS with disease patterns in different MS subtypes.

中文翻译：

原发性进行性多发性硬化症中视乳头周围高反射卵圆形肿块样结构与病程的相关性

视乳头周围高反射卵圆形块状结构 (PHOMS) 是多发性硬化症 (MS) 患者视网膜光学相干断层扫描期间的新发现。迄今为止，没有关于早期 MS 发生 PHOMS 的数据。本研究的目的是调查首次诊断为早期复发缓解型 MS (RRMS) 患者的 PHOMS 频率，并寻找 PHOMS 与不同 MS 亚型疾病模式的关联。

更新日期：2021-08-09

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