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Human Exposure to Environmental Pollutants and Associations with Non-Hodgkin Lymphoma: A Review
Exposure and Health ( IF 6.7 ) Pub Date : 2021-08-10 , DOI: 10.1007/s12403-021-00421-9
Rachael Grove 1 , Otto Sanchez 2
Affiliation  

The incidence rate of non-Hodgkin lymphoma (NHL) is currently increasing within Canada as well as worldwide. Environmental pollutants are ubiquitous in the environment and can potentially increase an individual’s risk of developing NHL. The goal of this literature review was to identify environmental pollutants associated with diagnosis of NHL and summarize their current levels in human populations. Sixteen environmental pollutants were identified as having associations with NHL diagnosis, including dichlorodiphenyltrichloroethane (DDT), pentachlorophenol (PCP), polychlorinated biphenyls (PCBs), carbon tetrachloride, and various pesticides. PCB levels in human breast milk were highest in developed countries, while DDT levels were highest in malaria-endemic countries. 2,4-Dichlorophenoxyacetic acid and glyphosate levels were highest in individuals who were occupationally exposed to these chemicals. Humans are mainly exposed to the identified pollutants through food. PCBs were found within animal products such as milk and cheese, and a variety of pesticides were found in various fruits and vegetables. Individuals who followed vegan and vegetarian diets had lower levels of non-pesticide pollutants in their body due to limited consumption of animal products but had higher pesticide levels due to increased consumption of fruits and vegetables. However, organic diets proved to mitigate this issue. Further research needs to be conducted on a wider variety of pollutants to gain a comprehensive understanding of the effects of these pollutants in association with NHL.



中文翻译:

人类对环境污染物的暴露以及与非霍奇金淋巴瘤的关联:综述

非霍奇金淋巴瘤 (NHL) 的发病率目前在加拿大和世界范围内都在增加。环境污染物在环境中无处不在,可能会增加个人患 NHL 的风险。本文献综述的目的是确定与 NHL 诊断相关的环境污染物,并总结它们在人群中的当前水平。有 16 种环境污染物被确定与 NHL 诊断有关,包括二氯二苯三氯乙烷 (DDT)、五氯苯酚 (PCP)、多氯联苯 (PCB)、四氯化碳和各种农药。发达国家的母乳中多氯联苯含量最高,而疟疾流行国家的滴滴涕含量最高。2、4-二氯苯氧乙酸和草甘膦水平在职业暴露于这些化学物质的个体中最高。人类主要通过食物接触到已识别的污染物。在牛奶和奶酪等动物产品中发现了多氯联苯,在各种水果和蔬菜中发现了多种杀虫剂。遵循纯素和素食饮食的个体由于动物产品的摄入量有限,体内非农药污染物的水平较低,但由于水果和蔬菜摄入量的增加,农药水平较高。然而,有机饮食证明可以缓解这个问题。需要对更广泛的污染物进行进一步研究,以全面了解这些污染物与 NHL 相关的影响。人类主要通过食物接触到已识别的污染物。在牛奶和奶酪等动物产品中发现了多氯联苯,在各种水果和蔬菜中发现了多种杀虫剂。遵循纯素和素食饮食的个体由于动物产品的摄入量有限,体内非农药污染物的水平较低,但由于水果和蔬菜摄入量的增加,农药水平较高。然而,有机饮食证明可以缓解这个问题。需要对更广泛的污染物进行进一步研究,以全面了解这些污染物与 NHL 相关的影响。人类主要通过食物接触到已识别的污染物。在牛奶和奶酪等动物产品中发现了多氯联苯,在各种水果和蔬菜中发现了多种杀虫剂。遵循纯素和素食饮食的人由于动物产品的摄入量有限,体内非农药污染物的含量较低,但由于水果和蔬菜的摄入量增加,农药含量较高。然而,有机饮食证明可以缓解这个问题。需要对更广泛的污染物进行进一步研究,以全面了解这些污染物与 NHL 相关的影响。在各种水果和蔬菜中发现了多种农药。遵循纯素和素食饮食的个体由于动物产品的摄入量有限,体内非农药污染物的水平较低,但由于水果和蔬菜摄入量的增加,农药水平较高。然而,有机饮食证明可以缓解这个问题。需要对更广泛的污染物进行进一步研究,以全面了解这些污染物与 NHL 相关的影响。在各种水果和蔬菜中发现了多种农药。遵循纯素和素食饮食的个体由于动物产品的摄入量有限,体内非农药污染物的水平较低,但由于水果和蔬菜摄入量的增加,农药水平较高。然而,有机饮食证明可以缓解这个问题。需要对更广泛的污染物进行进一步研究,以全面了解这些污染物与 NHL 相关的影响。

更新日期:2021-08-10
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