Background Imbalances in glucose and lipid metabolism in the background of a declining immune system, along with aging, make one prone to glucolipotoxicity-related diseases such as hepatic steatosis and to high risk of infection-related mortality, as with COVID-19, warranting a safe prophylactic measure to help regulate both metabolism and the immune system. Based on the beneficial effects of the AFO-202 strain of black yeast Aureobasidium pullulans-produced beta 1,3-1,6 glucan in balancing of blood glucose and immune enhancement, and that of the N-163 strain of the same species in lipid metabolism and immune modulation, in this pilot study, we have evaluated their specific benefits in healthy human subjects.

中文翻译：

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两种新型出芽短梗霉菌株产生的 Beta 1,3-1,6 葡聚糖对健康日本中年男性的免疫和代谢有益作用：一项探索性研究

背景在免疫系统下降和衰老的背景下，葡萄糖和脂质代谢的不平衡使人们容易患与糖脂毒性相关的疾病，如肝脂肪变性和感染相关死亡的高风险，如 COVID-19，需要有助于调节新陈代谢和免疫系统的安全预防措施。基于黑酵母Aureobasidium pullulans的 AFO-202 菌株产生的β 1,3-1,6 葡聚糖在平衡血糖和免疫增强方面的有益作用，以及同种的 N-163 菌株在脂质方面的有益作用代谢和免疫调节，在这项试点研究中，我们评估了它们对健康人类受试者的特定益处。