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Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure
Respiratory Medicine ( IF 4.3 ) Pub Date : 2021-08-10 , DOI: 10.1016/j.rmed.2021.106571
Francesco Vladimiro Segala 1 , Giacomo Sgalla 2 , Federica Salvati 1 , Ludovica Berardini 2 , Marcantonio Negri 3 , Elisabetta Nardella 3 , Annalisa Potenza 3 , Rita Murri 4 , Massimo Fantoni 4
Affiliation  

Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated with methylprednisolone 1mg/kg for showing clinical and radiological features suggestive of OP at least 20 days after symptom onset and despite standard treatment for COVID-19.



中文翻译:

辅助皮质类固醇治疗 COVID-19 持续性呼吸衰竭患者机化性肺炎

自 COVID-19 大流行开始以来,与病毒性机化性肺炎 (OP) 一致的临床、放射学和组织病理学特征已被报告为该病的标志性特征。在这里,我们描述了 10 名严重 COVID-19 肺炎患者的病例,这些患者在症状发作后至少 20 天,尽管对 COVID-19 进行了标准治疗,但仍显示出提示 OP 的临床和放射学特征,并接受了 1mg/kg 的甲泼尼龙治疗。

更新日期:2021-08-11
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