α-Tocopheramine has shown great promises as a stabilizer for synthetic and natural polymers, but is also investigated in various biomedical scenarios. Many studies have been hampered by the fact that the oxidation products of α-tocopheramine have not yet been properly identified and their analytical data are still lacking. In the present study, we synthesized and fully analytically characterized all N-oxidation products that can form upon oxidation of α-tocopheramine in aqueous media, including the hydroxylamine, nitroso, and nitro derivative, in this way providing standards for the identification of the so far elusive byproducts. Synthesis and stability of the derivatives are discussed.

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中文翻译：

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α-生育酚胺单体 N-氧化衍生物的合成和分析表征

α-生育酚已显示出作为合成和天然聚合物稳定剂的巨大希望，但也在各种生物医学场景中进行了研究。由于 α-生育酚胺的氧化产物尚未得到正确鉴定，且仍缺乏分析数据，因此许多研究受到阻碍。在本研究中，我们合成并完全分析表征了所有在水性介质中氧化 α-生育酚时可以形成的 N-氧化产物，包括羟胺、亚硝基和硝基衍生物，以此方式为鉴定这些产物提供了标准。难以捉摸的副产品。讨论了衍生物的合成和稳定性。

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