Anastomotic leak is the most feared complication of gastrointestinal surgery. Mesenchymal stem cell technology is used clinically to promote wound healing; however, the safety and efficacy of this technology on anastomotic healing has yet to be defined. The aim of this study was to investigate whether mesenchymal stem cells confer any benefit when applied to animal models for gastrointestinal anastomotic leak, identify the methodology and how efficacy is assessed.

中文翻译：

---

间充质干细胞在胃肠道吻合口瘘动物模型中的应用：系统评价

吻合口瘘是消化道手术中最可怕的并发症。间充质干细胞技术在临床上用于促进伤口愈合；然而，这项技术在吻合口愈合方面的安全性和有效性尚未确定。本研究的目的是调查间充质干细胞在应用于胃肠道吻合口漏的动物模型时是否带来任何益处，确定方法以及如何评估疗效。