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Identification of the metabolites of rhapontigenin in rat and human by ultra-high-performance liquid chromatography—high-resolution mass spectrometry
Rapid Communications in Mass Spectrometry ( IF 2 ) Pub Date : 2021-08-07 , DOI: 10.1002/rcm.9180
Jingzhi An 1 , Jie Yang 1 , Yuan Wei 1 , Yunsi Liu 2 , Yan Song 2 , Zuzhuo Zhang 2 , Ying Pan 3
Affiliation  

Rhapontigenin, a stilbene compound isolated from the medicinal plant of rhubarb rhizomes, has shown a variety of biological activities. The purpose of this study was to identify and characterize the metabolites of rhapontigenin in rat liver microsomes, hepatocytes, urine, and human liver microsomes and hepatocytes.

中文翻译:

超高效液相色谱-高分辨质谱法鉴定大鼠和人鼠李黄素代谢物

Rhapontigenin 是一种从大黄根茎药用植物中分离出来的芪化合物,具有多种生物活性。本研究的目的是鉴定和表征大鼠肝微粒体、肝细胞、尿液以及人肝微粒体和肝细胞中的 rhapontigenin 代谢物。
更新日期:2021-08-29
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