Genetic and functional analyses detect one pathological NFATC1 mutation in a Chinese tricuspid atresia family.,Molecular Genetics & Genomic Medicine

当前位置： X-MOL 学术 › Mol. Genet. Genomic Med. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Genetic and functional analyses detect one pathological NFATC1 mutation in a Chinese tricuspid atresia family.
Molecular Genetics & Genomic Medicine ( IF 2 ) Pub Date : 2021-08-07 , DOI: 10.1002/mgg3.1771
Bojian Li ₁ , Tingting Li ₁ , Tian Pu ₁ , Chunjie Liu ₁ , Sun Chen ₁ , Kun Sun ₁ , Rang Xu ₂

Affiliation

Cardiac valvulogenesis is a highly conserved process among vertebrates and cause unidirectional flow of blood in the heart. It was precisely regulated by signal pathways such as VEGF, NOTCH, and WNT and transcriptional factors such as TWIST1, TBX20, NFATC1, and SOX9. Tricuspid atresia refers to morphological deficiency of the valve and confined right atrioventricular traffic due to tricuspid maldevelopment, and is one of the most common types of congenital valve defects.

更新日期：2021-09-23

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>