Five-membered heterocyclic N-oxides attract special attention due to their significant potential applications in medicinal chemistry and advanced materials science. In this regard, novel methods for their synthesis and functionalization are in constant demand. In this short review, recent state-of-the-art achievements in the chemistry of isoxazoline N-oxides, 1,2,3-triazole 1-oxides and 1,2,5-oxadiazole 2-oxides are summarized. The main routes involving transition-metal-catalyzed and metal-free functionalization protocols along with mechanistic considerations are outlined. The transformations of these hetarene N-oxide rings as precursors to other nitrogen heterocyclic systems are also presented.1 Introduction2 Isoxazoline N-Oxides3 1,2,3-Triazole 1-Oxides4 1,2,5-Oxadiazole 2-Oxides5 Conclusion

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五元环戊二烯氮氧化物：合成和反应性的最新进展

五元杂环氮氧化物因其在药物化学和先进材料科学中的重要潜在应用而受到特别关注。在这方面，不断需要用于它们的合成和功能化的新方法。在这篇简短的评论中，总结了异恶唑啉 N-氧化物、1,2,3-三唑 1-氧化物和 1,2,5-恶二唑 2-氧化物化学方面的最新成果。概述了涉及过渡金属催化和无金属功能化协议以及机械考虑的主要途径。还介绍了这些杂环戊二烯 N-氧化物环作为其他氮杂环系统前体的转化。 1 引言 2 异恶唑啉 N-氧化物 3 1,2,3-三唑 1-氧化物 4 1,2,5-恶二唑 2-氧化物 5 结论