It is significant to develop a point-of-care testing (POCT) method for rapid detection of medicinal molecules. In this paper, a graphdiyne (GDY)-ionic liquid (IL) composite was prepared via one-step facile ultrasound preparation process and then modified on gold (Au) electrode surface by simple casting method. Scanning electron microscopy and transmission electron microscopy were used to characterize the morphology of GDY-IL composite. Cyclic voltammetric results proved that GDY-IL composite on the electrode surface could effectively improve electron transfer rate, which meant that GDY-IL composite had high conductivity with big surface area. Finally, the modified electrode exhibited excellent performances for rutin detection with wider linear range (8.0×10⁻⁹ mol L⁻¹–2.0×10⁻⁶ mol L⁻¹ and 2.0×10⁻⁶ mol L⁻¹–1.5×10⁻⁴ mol L⁻¹) and lower detection limit (2.7 nmol L⁻¹, 3S₀/S). The Nafion/GDY-IL/Au electrode showed good sensitivity and high selectivity, which was satisfactory in analytical application to real samples. Therefore, the GDY-IL composite modified electrode has the potential applications in the POCT for electrochemical analysis of various medicinal molecules.

中文翻译：

---

石墨二炔和离子液体复合修饰金电极用于芦丁的灵敏伏安分析

开发一种用于快速检测药物分子的即时检测 (POCT) 方法具有重要意义。在本文中，通过一步简便的超声制备工艺制备石墨二炔（GDY）-离子液体（IL）复合材料，然后通过简单的铸造方法在金（Au）电极表面改性。扫描电子显微镜和透射电子显微镜用于表征GDY-IL复合材料的形态。循环伏安结果证明，电极表面的GDY-IL复合材料可以有效提高电子转移速率，这意味着GDY-IL复合材料具有高导电性和大表面积。最后，修饰电极表现出优异的芦丁检测性能，具有更宽的线性范围（8.0×10 ^-9  mol L ^-1–2.0×10 ^-6  mol L ^-1和 2.0×10 ^-6  mol L ^-1 –1.5×10 ^-4  mol L ^-1）和检测下限（2.7 nmol L ^-1 , 3S ₀ /S）。Nafion/GDY-IL/Au电极表现出良好的灵敏度和高选择性，在实际样品的分析应用中令人满意。因此，GDY-IL 复合修饰电极在 POCT 中具有潜在的应用，可用于各种药物分子的电化学分析。