Formaldehyde reacts with amino acids in living organisms to form toxic intermediates that cause epithelial cell damage. In past epidemiological studies, a statistically significant relationship was found between FA and leukemia risks and occupational inhalation exposure. As a complementary and alternative medicine (CAM) technique or alternative medicine, shark cartilage (SC) and shark liver oil (SLO) are presented as a new and different alternative source in this study. In this study, the toxic effects of formaldehyde (FA) on lung and the protective effects of SC and SLO against these toxins have been investigated. For the experiment, 40 rats were classified as follows: 4, control group (experiment control); 6, the group that received FA but was not treated (treatment control); 15, the group that was given FA and SC for treatment; and the last 15 were the group that was given FA and SLO for treatment. Negative effects of FA on lung were evaluated biochemically, genetically and pathologically. In terms of therapeutic efficacy, SLO appears to be more effective in improving lung injury on the basis of genetic, pathological and biochemical findings, against to FA administration. The toxic effect of FA in lung and the therapeutic effect of SLO and SC were determined and we believe that our experimental model provided the desired goal and success on the basis of our work.

中文翻译：

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鲨鱼软骨 (SC) 和鲨鱼肝油 (SLO) 通过甲醛 (FA) 暴露治疗肺损伤

甲醛与生物体内的氨基酸反应形成有毒中间体，导致上皮细胞损伤。在过去的流行病学研究中，发现 FA 与白血病风险和职业吸入暴露之间存在统计学上的显着关系。作为一种补充和替代医学 (CAM) 技术或替代医学，鲨鱼软骨 (SC) 和鲨鱼肝油 (SLO) 在本研究中被列为新的不同替代来源。在这项研究中，研究了甲醛 (FA) 对肺的毒性作用以及 SC 和 SLO 对这些毒素的保护作用。为进行实验，将40只大鼠分为以下几类： 4、对照组（实验对照组）；6、接受FA但未治疗组（治疗对照）；15、FA和SC治疗组；最后 15 组是接受 FA 和 SLO 治疗的组。从生化、遗传和病理学方面评估 FA 对肺的负面影响。在治疗功效方面，SLO 似乎在遗传、病理和生化发现的基础上更有效地改善肺损伤，而不是 FA 给药。确定了 FA 在肺中的毒性作用以及 SLO 和 SC 的治疗效果，我们相信我们的实验模型在我们工作的基础上提供了预期的目标和成功。反对足协管理。确定了 FA 在肺中的毒性作用以及 SLO 和 SC 的治疗效果，我们相信我们的实验模型在我们工作的基础上提供了预期的目标和成功。反对足协管理。确定了 FA 在肺中的毒性作用以及 SLO 和 SC 的治疗效果，我们相信我们的实验模型在我们工作的基础上提供了预期的目标和成功。