In this work, a novel coordination polymer HNU-55 has been synthesized by the reaction of Zn(II) ion with the organic ligand 3-pyridinesulfonic acid (PSA) under solvothermal condition, which can be used as a fluorescent sensor for the detection of doxycycline (DOX). The fluorescent performance is effective in a wide linear range from 0 to 30 μM of DOX with a low detection limit of 3.7 nM. Likewise, the fluorescent sensor presents good selectivity, anti-interference, and circularity. Additionally, the HNU-55 sensor can be successfully used to assay the content of DOX in pig feed. Furthermore, the mechanism of fluorescence enhancement has been discussed in detail, which provides a clear understanding for the antibiotic detection based on the fluorescence enhancement.

中文翻译：

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基于荧光增强的多西环素选择性灵敏检测锌配位聚合物传感器

在这项工作中，通过 Zn(II) 离子与有机配体 3-吡啶磺酸 (PSA) 在溶剂热条件下反应合成了一种新型配位聚合物HNU-55，可用作荧光传感器检测强力霉素（DOX）。荧光性能在 0 到 30 μM DOX 的宽线性范围内有效，检测限低至 3.7 nM。同样，荧光传感器具有良好的选择性、抗干扰性和圆形度。此外，HNU-55传感器可成功用于检测猪饲料中 DOX 的含量。此外，详细讨论了荧光增强的机制，为基于荧光增强的抗生素检测提供了清晰的认识。