As the main pathogen threatening human and animal health, viruses can affect the immunity and metabolism of bodies. There are innate microbial barriers in the digestive tract of the body to preserve the homeostasis of the animal body, which directly or indirectly influences the host defence against viral infection. Understanding the interaction between viruses and intestinal microbiota or probiotics is helpful to study the pathogenesis of diseases. Here, we review recent studies on the interaction mechanism between intestinal microbiota and viruses. The interaction can be divided into two aspects: inhibition of viral infection by microbiota and promotion of viral infection by microbiota. The treatment of viral infection by probiotics is summarized.

作为威胁人类和动物健康的主要病原体，病毒会影响机体的免疫和新陈代谢。机体消化道存在先天的微生物屏障，以维持动物机体的稳态，直接或间接影响宿主对病毒感染的防御。了解病毒与肠道微生物群或益生菌之间的相互作用有助于研究疾病的发病机制。在这里，我们回顾了最近关于肠道微生物群与病毒相互作用机制的研究。相互作用可分为两个方面：微生物群抑制病毒感染和微生物群促进病毒感染。总结了益生菌治疗病毒感染的方法。