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Strategy for understanding the biological defense mechanism involved in immune priming in kuruma shrimp
Developmental & Comparative Immunology ( IF 2.9 ) Pub Date : 2021-08-04 , DOI: 10.1016/j.dci.2021.104228
Tohru Mekata 1
Affiliation  

Since the 1970s, individuals that survive a specific infectious disease among crustaceans reportedly develop resistance to the given virulence factors. Quasi-immune response is a similar phenomenon of acquired resistance against white spot syndrome virus, also found in kuruma shrimp. This phenomenon, resembling immunological memory, is collectively called immune priming and recently attracts increasing attention. In this study, I review, along with recent findings, past attempts to immunize shrimp by administration of the pathogen itself or recombinant proteins of viral constituent factors. Moreover, I aimed at investigating the diversity of pattern recognition receptors in kuruma shrimp from the currently available information that allows for a better understanding of immune priming. This review would potentially help to elucidate the underlying mechanisms of immune priming in the future.



中文翻译:

了解黧马虾免疫启动所涉及的生物防御机制的策略

据报道,自 1970 年代以来,在甲壳类动物中幸存下来的特定传染病的个体对给定的毒力因子产生了抗药性。准免疫反应是一种类似的对白斑综合征病毒的获得性抗性现象,这种现象也存在于 kuruma 虾中。这种类似于免疫记忆的现象统称为免疫启动,最近引起了越来越多的关注。在这项研究中,我回顾了过去通过施用病原体本身或病毒成分因子的重组蛋白对虾进行免疫的尝试以及最近的发现。此外,我的目标是从目前可用的信息中研究 kuruma 虾中模式识别受体的多样性,以便更好地了解免疫启动。

更新日期:2021-08-09
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