Among the established risk factors associated with developing rheumatoid arthritis (RA), smoking remains one of the leading environmental exposures associated with disease onset. One meta-analysis of ten studies found that the risk of developing RA increased by 26% among those who smoked 1-10 pack-years, and nearly doubled among those with more than 20 pack-years, compared to never smokers[1]. Studies that closely examine smoking and development of RA continue to be important, as it is a modifiable risk factor that can significantly reduce the burden of disease in the population.

中文翻译：

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哪里有烟，哪里就有关节：被动吸烟和类风湿性关节炎

在与发生类风湿性关节炎 (RA) 相关的既定风险因素中，吸烟仍然是与疾病发作相关的主要环境暴露因素之一。一项针对十项研究的荟萃分析发现，与从不吸烟的人相比，吸烟 1-10 包年的人患 RA 的风险增加了 26%，而吸烟超过 20 包年的人患 RA 的风险几乎翻了一番[1]。密切检查吸烟和类风湿性关节炎发展的研究仍然很重要，因为它是一种可改变的风险因素，可以显着降低人群的疾病负担。