This work presents a highly efficient catalytic hydrogenation system developed for the selective transformation of tertiary N,N-dimethyldodecanamide and secondary azepan-2-one amides to the corresponding amines. Industrial hydrogenation catalysts Pd/Al₂O₃, Pt/Al₂O₃ and Rh/Al₂O₃ were modified with vanadium (V) or molybdenum (Mo) species as oxophilic centres. The modified catalysts were prepared by deposition of V or Mo precursor on supported catalysts via impregnation method. The catalysts were characterized by ICP-OES, XRD, XPS, H₂-TPR, FTIR, CO-chemisorption, TEM, SEM-EDX and TGA. Modified Rh-V/Al₂O₃ catalyst displayed the best performance affording high yield and selectivity >95 % to the desired tertiary and secondary amines at moderate reaction conditions of T < 130 °C and P_H2 < 50 bar. The strong synergistic interaction and proximity of hydrogenation Rh⁰ sites and oxophilic V^δ+ sites in the bimetallic Rh-V/Al₂O₃ catalyst were determined to be beneficial for the selective dissociation of CO bond of the carboxamides into the desired amines.

这项工作提出了一种高效的催化氢化系统，用于将叔N,N-二甲基十二酰胺和仲 azepan-2-one 酰胺选择性转化为相应的胺。工业加氢催化剂Pd/Al ₂ O ₃、Pt/Al ₂ O ₃和Rh/Al ₂ O ₃用钒（V）或钼（Mo）物质作为亲氧中心改性。通过浸渍法在负载型催化剂上沉积 V 或 Mo 前驱体制备改性催化剂。通过ICP-OES、XRD、XPS、H ₂ -TPR、FTIR、CO-化学吸附、TEM、SEM-EDX和TGA对催化剂进行了表征。改性 Rh-V/Al ₂ O₃催化剂显示出最佳性能，在 T < 130 °C 和 P _H2 < 50 bar 的温和反应条件下，对所需的叔胺和仲胺提供了高产率和 >95% 的选择性。双金属Rh-V/Al ₂ O ₃催化剂中氢化Rh ⁰位点和亲氧性V ^δ+位点的强协同相互作用和接近性被确定有利于羧酰胺的CO 键选择性离解成所需的胺。