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Organic-Molecule-Based Fluorescent Chemosensor for Nerve Agents and Organophosphorus Pesticides
Topics in Current Chemistry ( IF 8.6 ) Pub Date : 2021-08-04 , DOI: 10.1007/s41061-021-00345-7
Muskan Gori 1 , Ashima Thakur 1 , Abha Sharma 1 , S J S Flora 2
Affiliation  

Organophosphorus (OP) compounds are typically a broad class of compounds that possess various uses such as insecticides, pesticides, etc. One of the most evil utilizations of these compounds is as chemical warfare agents, which pose a greater threat than biological weapons because of their ease of access. OP compounds are highly toxic compounds that cause irreversible inhibition of enzyme acetylcholinesterase, which is essential for hydrolysis of neurotransmitter acetylcholine, leading to series of neurological disorders and even death. Due to the extensive use of these organophosphorus compounds in agriculture, there is an increase in the environmental burden of these toxic chemicals, with severe environmental consequences. Hence, the rapid and sensitive, selective, real-time detection of OP compounds is very much required in terms of environmental protection, health, and survival. Several techniques have been developed over a few decades to easily detect them, but still, numerous challenges and problems remain to be solved. Major advancement has been observed in the development of sensors using the spectroscopic technique over recent years because of the advantages offered over other techniques, which we focus on in the presented review.

Graphic Abstract



中文翻译:

用于神经毒剂和有机磷农药的有机分子荧光化学传感器

有机磷 (OP) 化合物通常是一大类化合物,具有多种用途,例如杀虫剂、杀虫剂等。这些化合物最邪恶的用途之一是作为化学战剂,由于其具有的化学战剂,它比生物武器构成更大的威胁。四通八达的交通网络。OP化合物是剧毒化合物,会导致乙酰胆碱酯酶的不可逆抑制,乙酰胆碱酯酶对神经递质乙酰胆碱的水解至关重要,导致一系列神经系统疾病甚至死亡。由于这些有机磷化合物在农业中的广泛使用,这些有毒化学品的环境负担增加,对环境造成严重后果。因此,快速、灵敏、有选择性、从环境保护、健康和生存的角度来看,实时检测OP化合物是非常需要的。几十年来,已经开发了多种技术来轻松检测它们,但仍有许多挑战和问题有待解决。近年来,由于与其他技术相比具有优势,因此在使用光谱技术开发传感器方面取得了重大进展,我们在本文中重点介绍了这些优势。

图形摘要

更新日期:2021-08-04
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