The rapid growth in the global human population has increased the prevalence of emerging infectious diseases, which poses a major risk to public health. In search of effective clinical solutions, the acquisition of knowledge and understanding of biomolecular processes associated with viral pathogens represents a prerequisite. In this context, biophysical engineering approaches are particularly promising since they can resolve biomolecular interactions systematically by circumventing the complexities associated with experiments involving natural biological systems. The engineering approaches encompass the design and construction of biomimetic platforms that simulate the physiological system. This approach enables us to characterize, measure, and quantitatively analyze biomolecular interactions.

中文翻译：

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抗病毒药物开发的生物物理测量策略：病毒模拟平台的最新进展到单粒子水平

全球人口的快速增长增加了新发传染病的流行，这对公共卫生构成了重大威胁。在寻找有效的临床解决方案时，获得与病毒病原体相关的生物分子过程的知识和理解是一个先决条件。在这种情况下，生物物理工程方法特别有前途，因为它们可以通过规避与涉及自然生物系统的实验相关的复杂性来系统地解决生物分子相互作用。工程方法包括模拟生理系统的仿生平台的设计和构建。这种方法使我们能够表征、测量和定量分析生物分子相互作用。