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Heart, kidney and left ventricular assist device: a complex trio
European Journal of Clinical Investigation ( IF 5.5 ) Pub Date : 2021-08-04 , DOI: 10.1111/eci.13662
Alessia Gambaro 1 , Gianmarco Lombardi 2 , Francesco Onorati 3 , Leonardo Gottin 4 , Flavio Luciano Ribichini 1
Affiliation  

Heart failure (HF) is a complex syndrome affecting the whole body, kidneys included. The left ventricular assist device (LVAD) is a valid option for patients with very severe HF. Focusing on renal function, LVAD implantation could theoretically reverse the detrimental effects of HF syndrome on kidneys. However, implanting an LVAD is a high-risk surgical procedure, and LVAD patients have higher risk of bleeding, device thrombosis, strokes, renal impairment, multi-organ failure and infections. Furthermore, an LVAD has its own particular effects on the renal system.

中文翻译:

心脏、肾脏和左心室辅助装置:一个复杂的三重奏

心力衰竭 (HF) 是一种影响全身的复杂综合征,包括肾脏。左心室辅助装置 (LVAD) 是非常严重的 HF 患者的有效选择。着眼于肾功能,LVAD 植入理论上可以逆转 HF 综合征对肾脏的不利影响。然而,植入 LVAD 是一种高风险的外科手术,LVAD 患者有较高的出血、装置血栓形成、中风、肾功能损害、多器官衰竭和感染的风险。此外,LVAD 对肾脏系统有其自身的特殊影响。
更新日期:2021-08-04
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