Water compatible supramolecular polymers (WCSPs) combine aqueous compatibility with the reversibility and environmental responsiveness of supramolecular polymers. WCSPs have seen application across a number of fields, including stimuli-responsive materials, healable materials, and drug delivery, and are attracting increasing attention from the design, synthesis, and materials perspectives. In this review, we summarize the chemistry of WCSPs from 2016 to mid-2021. For the sake of discussion, we divide WCSPs into five categories based on the core supramolecular approaches at play, namely hydrogen-bonding arrays, electrostatic interactions, large π-conjugated subunits, host–guest interactions, and peptide-based systems, respectively. We discuss both synthesis and polymer structure, as well as the underlying design expectations. The goal of this overview is to deepen our understanding of the strategies that have been exploited to prepare WCSPs, as well as their properties and uses. Thus, a section devoted to potential applications is included in this review.

中文翻译：

---

与水相容的超分子聚合物：最新进展

与水相容的超分子聚合物 ( WCSP ) 将水相相容性与超分子聚合物的可逆性和环境响应性相结合。WCSP已在多个领域得到应用，包括刺激响应材料、可愈合材料和药物递送，并且在设计、合成和材料方面越来越受到关注。在这篇综述中，我们总结了2016 年至 2021 年中期WCSP的化学性质。为了便于讨论，我们将WCSP划分为根据发挥作用的核心超分子方法分为五类，分别是氢键阵列、静电相互作用、大π-共轭亚基、主客体相互作用和基于肽的系统。我们讨论了合成和聚合物结构，以及潜在的设计预期。本概述的目的是加深我们对用于准备WCSP的策略及其特性和用途的理解。因此，本次审查中包含了一个专门讨论潜在应用的部分。