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Physiological Parameters to Identify Suitable Blood Donor Cows for Preparation of Platelet Rich Plasma
Animals ( IF 3 ) Pub Date : 2021-08-04 , DOI: 10.3390/ani11082296
Anna Lange-Consiglio 1 , Rosangela Garlappi 2 , Chiara Spelta 3 , Antonella Idda 1 , Stefano Comazzi 1 , Rita Rizzi 1 , Fausto Cremonesi 1
Affiliation  

Platelet rich plasma (PRP) has been shown to be beneficial in the treatment of bovine mastitis, with an action comparable to that of antibiotics. Autologous treatment is feasible in experimental conditions but is difficult to apply in field conditions, particularly in acute mastitis. The ideal scenario would be to have heterologous PRP stored on every farm so that it is readily available when needed. In this paper, we analysed data collected during bovine mastitis treatment with heterologous PRP produced by casual donor cows on several farms. We tried to identify parameters which might be useful to identify the most suitable cows to be used as blood donors, to obtain the highest yield of PRP. Variables considered for each animal were the age, the parity, the date of the last parturition, the season of blood collection, the site of blood collection (jugular or mammary vein) and the reproductive status e.g., pregnant or not pregnant. There were statistically significant differences for all the variables considered from the 135 blood cows, except for the blood collection season. The highest yield of PRP was associated with nonpregnancy blood collection within three months of parturition, parity 3 or 4, and blood collection from the mammary vein.

中文翻译:

确定用于制备富血小板血浆的合适献血牛的生理参数

富含血小板的血浆 (PRP) 已被证明对治疗牛乳腺炎有益,其作用与抗生素相当。自体治疗在实验条件下是可行的,但在野外条件下难以应用,特别是在急性乳腺炎中。理想的情况是将异源 PRP 存储在每个农场中,以便在需要时随时可用。在本文中,我们分析了在几个农场使用由临时供体奶牛生产的异源 PRP 治疗牛乳腺炎期间收集的数据。我们试图确定可能有助于确定最适合用作献血者的奶牛的参数,以获得最高的 PRP 产量。为每只动物考虑的变量是年龄、胎次、最后一次分娩的日期、采血季节、采血部位(颈静脉或乳腺静脉)和生殖状态,例如怀孕或未怀孕。除了采血季节外,从 135 头血牛中考虑的所有变量都存在统计学上的显着差异。PRP 的最高产量与分娩后三个月内的非妊娠采血、第 3 次或第 4 次胎次以及从乳腺静脉采血有关。
更新日期:2021-08-04
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