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Curcumol inhibits ferritinophagy to restrain hepatocyte senescence through YAP/NCOA4 in non-alcoholic fatty liver disease
Cell Proliferation ( IF 8.5 ) Pub Date : 2021-08-03 , DOI: 10.1111/cpr.13107
Xiaoyu Qi 1 , Anping Song 1 , Mingyue Ma 1 , Peipei Wang 1 , Xinbei Zhang 1 , Chunfeng Lu 2 , Junxiu Zhang 1 , Shuguo Zheng 1 , Huanhuan Jin 1
Affiliation  

In recent years, cellular senescence has attracted a lot of interest in researchers due to its involvement in non-alcoholic fatty liver disease (NAFLD). However, the mechanism of cellular senescence is not clear. The purpose of this study was to investigate the effect of curcumol on hepatocyte senescence in NAFLD and the molecular mechanisms implicated.

中文翻译:

在非酒精性脂肪肝中,姜黄素通过 YAP/NCOA4 抑制铁蛋白吞噬抑制肝细胞衰老

近年来,细胞衰老因其参与非酒精性脂肪性肝病(NAFLD)而引起了研究人员的极大兴趣。然而,细胞衰老的机制尚不清楚。本研究的目的是研究姜黄醇对 NAFLD 肝细胞衰老的影响及其涉及的分子机制。
更新日期:2021-09-20
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