Aortic arterial stiffness is a strong independent predictor of cardiovascular disease (CVD); however, its dependence on mean arterial pressure (MAP) limits its clinical utility. The aortic-femoral arterial stiffness gradient (af-SG), a novel marker of CVD risk, may be a promising alternative, but its dependence on MAP is not known. The aim of this study was to determine the relationship between MAP and the af-SG in healthy older adults and those with established disease, including hypertension and diabetes.

中文翻译：

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老年人的主动脉-股动脉硬度梯度与血压无关：社区动脉粥样硬化风险 (ARIC) 研究。

主动脉僵硬度是心血管疾病 (CVD) 的一个强有力的独立预测因素；然而，它对平均动脉压（MAP）的依赖性限制了其临床应用。主动脉-股动脉硬度梯度 (af-SG) 是一种新的 CVD 风险标记，可能是一个有前途的替代方案，但其对 MAP 的依赖性尚不清楚。本研究的目的是确定健康老年人和患有高血压和糖尿病等既定疾病的老年人中 MAP 和 af-SG 之间的关系。