Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis.,Protein & Cell

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Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis.
Protein & Cell ( IF 21.1 ) Pub Date : 2021-08-03 , DOI: 10.1007/s13238-021-00860-9
Jinghui Lei _{1,

2} , Xiaoyu Jiang _{3,

4} , Wei Li _{1,

2} , Jie Ren _{4,

5,

6,

7} , Datao Wang ₈ , Zhejun Ji _{6,

9,

10} , Zeming Wu _{3,

6,

10} , Fang Cheng _{4,

11} , Yusheng Cai _{3,

6,

10} , Zheng-Rong Yu ₁₂ , Juan Carlos Izpisua Belmonte ₁₃ , Chunyi Li ₈ , Guang-Hui Liu _{1,

3,

4,

6,

10} , Weiqi Zhang _{4,

5,

6,

7} , Jing Qu _{4,

6,

9,

10} , Si Wang _{1,

2,

3}

Affiliation

Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.
CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.
Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China.
China National Center for Bioinformation, Beijing, 100101, China.
Institute of Antler Science and Product Technology, Changchun Sci-Tech University, Changchun, 130000, China.
State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China.
National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Department of Orthopaedics, Peking University First Hospital, Beijing, 100034, China.
Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.