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Exploration of GO-CuO nanocomposite for its antibacterial properties and potential application as a chemosensor in the sensing of L-Leucine
Inorganic and Nano-Metal Chemistry ( IF 1.7 ) Pub Date : 2021-08-03 , DOI: 10.1080/24701556.2021.1956958
R. Blessy Pricilla 1 , N. Bhuvanesh 2 , B. Vidhya 1 , S. Murugan 3 , R. Nandhakumar 2
Affiliation  

Abstract

Graphene known as the wonder material and finds its utilization in various applications including sensors.This work reports the solvothermal route and the chemical reflux method synthesis of graphene oxide copper oxide nanocomposite material (GO-CuO). The hitherto prepared GO-CuO nanocomposite was well characterized using the usual spectroscopic and microscopic technique such as Fourier transform infrared (FTIR) spectroscopy, Scanning electron microscopy (SEM), X-ray diffraction (XRD), UV-Vis Spectroscopy (UV), Photoluminescence Spectroscopy(PL) etc. The prepared GO-CuO nanocomposite was found to selectively bind to L-Leucine without any interference from the other naturally occurring L-amino acids as a potential fluorescent chemosensor. The interference studies, effect of time, effect of pH and various equivalence studies were also performed for the GO-CuO nanocomposite with L-Leucine. The antibacterial activity of GO-CuO nanocomposite revealed a minimum inhibitory zone concentration for Methicillin Resistant Staphylococcus aureus to be 200 μg/ml, whereas for A. baumannii it was found to be 100 μg/ml.



中文翻译:

探索 GO-CuO 纳米复合材料的抗菌性能和作为 L-亮氨酸传感化学传感器的潜在应用

摘要

石墨烯被称为神奇材料,并在包括传感器在内的各种应用中得到应用。这项工作报告了氧化石墨烯氧化铜纳米复合材料 (GO-CuO) 的溶剂热路线和化学回流法合成。迄今为止制备的 GO-CuO 纳米复合材料使用常用的光谱和显微技术进行了很好的表征,例如傅里叶变换红外 (FTIR) 光谱、扫描电子显微镜 (SEM)、X 射线衍射 (XRD)、紫外-可见光谱 (UV)、光致发光光谱(PL)等。发现制备的GO-CuO纳米复合材料选择性地结合L-亮氨酸,而不受其他天然存在的L-氨基酸的干扰,作为一种潜在的荧光化学传感器。干扰研究,时间的影响,还对具有 L-亮氨酸的 GO-CuO 纳米复合材料进行了 pH 的影响和各种等效性研究。GO-CuO纳米复合材料的抗菌活性揭示了耐甲氧西林的最小抑菌区浓度金黄色葡萄球菌为 200 μg/ml,而鲍曼不动杆菌为 100 μg/ml。

更新日期:2021-08-03
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