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Fit in your genes: an introduction to genes and epigenetics for forensic practitioners
Journal of Forensic Practice Pub Date : 2021-08-04 , DOI: 10.1108/jfp-03-2021-0009
Jamie Stephen Walton 1
Affiliation  

Purpose

This paper aims to provide a brief and accessible introduction to genetics and epigenetics for forensic practitioners. It provides two primers which define key genetic concepts and explain what epigenetic mechanisms actually are. The primers are provided alongside sections that focus on genetic research relevant to forensic practice, with a range of key messages that support the call to contextualise harmful behaviour and build better awareness of gene-environment relationships.

Design/methodology/approach

This is an opinion paper.

Findings

Select and seminal studies from the genetic literature that have forensic practice relevance are cited. These include studies from candidate gene research and epigenetic research. They highlight a number of key themes, including the way neurodevelopment and behaviour are contextually adjusted to fit certain environments, with epigenetic changes being an underpinning biological mechanism that facilitates this.

Research limitations/implications

This article aims to introduce forensic practitioners to basic concepts in genetics and epigenetics so that they are able to engage with the relevant literature and understand the far-reaching implications for forensic practice.

Practical implications

It is becoming increasingly useful for forensic practitioners to appreciate how life experiences are encoded into biology through epigenetics. This paper highlights the potential of genetic and epigenetic research to provide major contributions to real-world practice in the coming years. It provides a modern biopsychosocial perspective on harmful behaviour and helps deepen the understanding of our efforts to support behaviour change. It offers ways to think of social and rehabilitative initiatives in biological terms.

Originality/value

This paper is one of few modern texts that focusses on the relevance of genetic and epigenetic research in applied forensic practice. It aims to introduce relevant concepts in an accessible manor. It intends to introduce biologically informed ways of understanding harmful behaviour within context and with attention to its function. It contributes to a de-pathologising narrative.



中文翻译:

适合您的基因:法医从业者的基因和表观遗传学介绍

目的

本文旨在为法医从业人员提供有关遗传学和表观遗传学的简短易懂的介绍。它提供了两个引物,它们定义了关键的遗传概念并解释了表观遗传机制究竟是什么。这些入门书与专注于与法医实践相关的基因研究的部分一起提供,其中包含一系列关键信息,支持将有害行为背景化并建立对基因-环境关系的更好认识。

设计/方法/方法

这是一篇意见书。

发现

引用了具有法医实践相关性的遗传文献中的精选和开创性研究。其中包括候选基因研究和表观遗传研究。他们强调了许多关键主题,包括根据环境调整神经发育和行为以适应特定环境的方式,表观遗传变化是促进这一点的基础生物学机制。

研究限制/影响

本文旨在向法医从业人员介绍遗传学和表观遗传学的基本概念,以便他们能够参与相关文献并了解对法医实践的深远影响。

实际影响

对于法医从业者来说,了解如何通过表观遗传学将生活经历编码到生物学中变得越来越有用。本文强调了遗传和表观遗传研究在未来几年为现实世界的实践做出重大贡献的潜力。它提供了关于有害行为的现代生物心理社会观点,并有助于加深对我们支持行为改变的努力的理解。它提供了从生物学角度思考社会和康复计划的方法。

原创性/价值

这篇论文是为数不多的专注于遗传和表观遗传研究在应用法医实践中的相关性的现代文本之一。它旨在以通俗易懂的方式介绍相关概念。它旨在引入生物学上了解有害行为的方法,并关注其功能。它有助于去病态的叙述。

更新日期:2021-09-21
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