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Future trends in magnetic source device design for magnetic targeted drug delivery system
International Journal of Applied Electromagnetics and Mechanics ( IF 0.6 ) Pub Date : 2021-07-30 , DOI: 10.3233/jae-210021
Qi Xiong 1, 2 , Xianqi Song 1, 2 , Meng Yang 1, 2, 3 , Lijun Zhou 1, 2 , Zhe Li 1, 2 , Xinhui Zhu 1, 2 , Li Zhi 1, 2
Affiliation  

Magnetic targeted drug delivery systems can improve drug utilization and reduce drug side effects. There are still many difficulties to be overcome in clinical practice. The main problems include providing large enough magnetic capture particles to concentrate drug-loaded magnetic micro-nanoparticles (MNPs) to the lesion site. The existing research focuses on the development of targeted carriers, and the magnet device has not formed a mature research system. Based on the recent development of magnet devices in recent years, this paper proposes the research direction of potential magnet devices. From the dynamic behavior of the particles under the magnetic field, the magnetic system and the mathematical model design direction of the optimized magnet are developed. This article describes the obstacles encountered in drug targeting in the study of magnet devices and summarizes the potential development of future magnet devices.

中文翻译:

磁性靶向给药系统磁源装置设计的未来趋势

磁性靶向给药系统可以提高药物利用率并减少药物副作用。在临床实践中还有许多困难需要克服。主要问题包括提供足够大的磁性捕获颗粒以将载药磁性微纳米颗粒 (MNP) 集中到病变部位。现有研究侧重于靶向载体的开发,磁体装置尚未形成成熟的研究体系。本文根据近年来磁体装置的最新发展,提出了潜在磁体装置的研究方向。从粒子在磁场作用下的动力学行为出发,提出了优化磁体的磁系统和数学模型设计方向。
更新日期:2021-08-03
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