Tecoflex® polyurethane catheters were surficial modified with acrylic acid (AAc) to obtain a hydrophilic material able to host antimicrobial agents. The grafted catheters were prepared by the oxidative pre-irradiation technique using ⁶⁰Co as the gamma-ray source. Graft kinetics was studied by varying the applied dose and the reaction time to obtain catheters with different grafting yields. Modified catheters were characterized by infrared spectroscopy (FTIR-ATR), thermogravimetric analysis (TGA), Cross-polarization Magic-angle spinning nuclear magnetic resonance in solid-state (CP/MAS ¹³C NMR), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS). The modified catheters displayed notable hydrophilicity absorbing water; besides, they exhibited a critical pH of 6.5 because of grafting presence. The graft endowed the catheters with the ability to load silver nanoparticles acquiring biocidal properties with the ability to prevent bacterial proliferation on its surface. Silver-impregnated catheters showed notable antimicrobial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) bacteria, presenting inhibiting halos of 8.1 and 10.2 mm on the catheter surroundings, respectively. The biocide property was confirmed when silver-impregnated catheters were challenged in a killing test against both bacteria, eradicating up to 80% of the bacterial population depending on the amount of loaded silver NPs.

Tecoflex® 聚氨酯导管用丙烯酸 (AAc) 进行表面改性，以获得能够承载抗菌剂的亲水材料。移植导管采用氧化预辐照技术制备，使用⁶⁰ Co 作为伽马射线源。通过改变应用剂量和反应时间来研究移植动力学，以获得具有不同移植产率的导管。改进的导管通过红外光谱 (FTIR-ATR)、热重分析 (TGA)、固态交叉极化魔角旋转核磁共振 (CP/MAS ¹³C NMR)、扫描电子显微镜 (SEM)、X 射线光电子能谱 (XPS)。改进后的导管显示出显着的亲水性吸水；此外，由于存在接枝，它们的临界 pH 值为 6.5。移植物赋予导管加载银纳米粒子的能力，从而获得杀生物特性，并能够防止其表面的细菌增殖。浸银导管对大肠杆菌（E.coli）和金黄色葡萄球菌（S.aureus）显示出显着的抗菌活性) 细菌，分别在导管周围呈现 8.1 和 10.2 毫米的抑制光晕。当银浸渍导管在针对两种细菌的​​杀灭试验中受到挑战时，杀菌剂的特性得到证实，根据负载的银 NPs 的数量，可消灭多达 80% 的细菌种群。