Impaired motor learning in individuals with Parkinson's disease is often attributed to deficits in executive function, which serves as an important cognitive process supporting motor learning. However, less is known about the role of other cognitive domains and its association with motor learning in Parkinson's disease. The objective of this study was to investigate the associations between motor learning and multiple domains of cognitive performance in individuals with Parkinson's disease. Twenty-nine participants with Parkinson's disease received comprehensive neuropsychological testing, followed by practice of a bimanual finger sequence task. A retention test of the finger sequence task was completed 24 h later. Hierarchical linear regressions were used to examine the associations between motor learning (acquisition rate and retention) and cognitive performance in five specific cognitive domains, while controlling for age, sex, and years of Parkinson's disease diagnosis. We found that a higher acquisition rate was associated with better episodic memory, specifically better recall in visual episodic memory, in individuals with Parkinson's disease. No significant associations were observed between retention and cognitive performance in any domains. The association between motor acquisition and episodic memory indicates an increased dependency on episodic memory as a potential compensatory cognitive strategy used by individuals with Parkinson's disease during motor learning.

中文翻译：

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帕金森病队列中的认知和运动学习：情景记忆中回忆的重要性。

帕金森病患者的运动学习受损通常归因于执行功能缺陷，而执行功能是支持运动学习的重要认知过程。然而，人们对其他认知领域的作用及其与帕金森病运动学习的关系知之甚少。本研究的目的是调查帕金森病患者运动学习与多个认知表现领域之间的关联。二十九名患有帕金森病的参与者接受了全面的神经心理学测试，然后进行了双手手指序列任务的练习。24小时后完成手指序列任务的保留测试。使用分层线性回归来检查运动学习（习得率和保留率）与五个特定认知领域的认知表现之间的关联，同时控制年龄、性别和帕金森病诊断年限。我们发现，对于帕金森病患者来说，较高的习得率与更好的情景记忆相关，特别是更好的视觉情景记忆回忆。在任何领域中，记忆力和认知表现之间都没有观察到显着的关联。运动习得和情景记忆之间的关联表明，帕金森病患者在运动学习过程中对情景记忆的依赖性增加，作为一种潜在的补偿性认知策略。