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Inflammatory bowel disease: An Indian perspective
Indian Journal of Medical Research ( IF 4.2 ) Pub Date : 2021-04-01 , DOI: 10.4103/ijmr.ijmr_936_18
Mayank Jain 1 , Jayanthi Venkataraman 1
Affiliation  

Inflammatory bowel disease (IBD) in recent times is causing a significant healthcare burden as both ulcerative colitis and Crohn's disease (CD) require lifelong therapy and constant monitoring. The current review highlights the concerns in a country like India with special reference to the changing trends of IBD, risk attribution and the financial issues. Indian immigrants behave like residential Indians, whereas their children show IBD prevalence similar to the West, highlighting the role of environmental triggers. However, the environmental and genetic factors in Indians with IBD are not well understood. Men appear to be more frequently affected than women in India. The disease severity is milder in the patients, both males and females, but the risk for colorectal cancer (CRC) is similar to the West. The incidence of paediatric IBD is on the rise. The major burden of IBD in the Indian subcontinent at present is in children, adolescents and teens. Cost towards the management of complications, non-adherence to treatment, differentiating tuberculosis from CD and finally screening for CRC in patients with IBD are the points to ponder in the Indian scenario.

中文翻译:

炎症性肠病:印度视角

由于溃疡性结肠炎和克罗恩病 (CD) 都需要终生治疗和持续监测,因此炎症性肠病 (IBD) 近来造成了重大的医疗保健负担。当前的审查强调了像印度这样的国家的担忧,特别提到了 IBD 的变化趋势、风险归因和财务问题。印度移民表现得像居住的印度人,而他们的孩子表现出与西方相似的 IBD 患病率,突出了环境触发因素的作用。然而,印度人 IBD 的环境和遗传因素尚不清楚。在印度,男性似乎比女性更容易受到影响。男性和女性患者的疾病严重程度较轻,但结直肠癌 (CRC) 的风险与西方相似。儿童 IBD 的发病率呈上升趋势。目前印度次大陆 IBD 的主要负担是儿童、青少年和青少年。在印度的情景中,并发症的管理、不坚持治疗、区分结核病与 CD 以及最终筛查 IBD 患者的 CRC 的成本是需要考虑的问题。
更新日期:2021-04-01
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