Impaired awareness of hypoglycaemia (IAH) affects about 25% of patients with type 1 diabetes (T1DM). IAH can be reversed by strict avoidance of hypoglycaemia for at least 3 weeks. Adjunctive treatment with sodium glucose cotransporter 2 inhibitors may reduce the risk of hypoglycaemia through reduction of glucose variability. We tested the hypothesis that short-term use of dapagliflozin may improve awareness of hypoglycaemia in people with T1DM and IAH.

中文翻译：

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短期使用达格列净对 1 型糖尿病患者低血糖意识受损的影响

约 25% 的 1 型糖尿病 (T1DM) 患者对低血糖 (IAH) 的认识受损。IAH 可以通过严格避免低血糖至少 3 周来逆转。钠葡萄糖协同转运蛋白 2 抑制剂的辅助治疗可通过降低葡萄糖变异性来降低低血糖风险。我们检验了短期使用达格列净可以提高 T1DM 和 IAH 患者对低血糖的认识的假设。