We have developed the bispectral electroencephalography (BSEEG) method for detection of delirium and prediction of poor outcomes.

To improve the BSEEG method by introducing a new EEG device.

In a prospective cohort study, EEG data were obtained and BSEEG scores were calculated. BSEEG scores were filtered on the basis of standard deviation (s.d.) values to exclude signals with high noise. Both non-filtered and s.d.-filtered BSEEG scores were analysed. BSEEG scores were compared with the results of three delirium screening scales: the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU), the Delirium Rating Scale-Revised-98 (DRS) and the Delirium Observation Screening Scale (DOSS). Additionally, the 365-day mortalities and the length of stay (LOS) in the hospital were analysed.

We enrolled 279 elderly participants and obtained 620 BSEEG recordings; 142 participants were categorised as BSEEG-positive, reflecting slower EEG activity. BSEEG scores were higher in the CAM-ICU-positive group than in the CAM-ICU-negative group. There were significant correlations between BSEEG scores and scores on the DRS and the DOSS. The mortality rate of the BSEEG-positive group was significantly higher than that of the BSEEG-negative group. The LOS of the BSEEG-positive group was longer compared with that of the BSEEG-negative group. BSEEG scores after s.d. filtering showed stronger correlations with delirium screening scores and more significant prediction of mortality.

We confirmed the usefulness of the BSEEG method for detection of delirium and of delirium severity, and prediction of patient outcomes with a new EEG device.

我们开发了用于检测谵妄和预测不良结果的双谱脑电图 (BSEEG) 方法。

通过引入新的 EEG 设备来改进 BSEEG 方法。

在一项前瞻性队列研究中，获得了脑电图数据并计算了 BSEEG 评分。基于标准偏差 (sd) 值过滤 BSEEG 分数以排除具有高噪声的信号。分析了未过滤和 sd 过滤的 BSEEG 分数。将 BSEEG 评分与三个谵妄筛查量表的结果进行比较：重症监护病房 (CAM-ICU) 的混淆评估方法、谵妄评定量表 - 修订版 - 98 (DRS) 和谵妄观察筛查量表 (DOSS)。此外，还分析了 365 天的死亡率和住院时间 (LOS)。

我们招募了 279 名老年参与者，并获得了 620 条 BSEEG 记录；142 名参与者被归类为 BSEEG 阳性，反映脑电图活动较慢。CAM-ICU 阳性组的 BSEEG 评分高于 CAM-ICU 阴性组。BSEEG 评分与 DRS 和 DOSS 评分之间存在显着相关性。BSEEG阳性组的死亡率明显高于BSEEG阴性组。与 BSEEG 阴性组相比，BSEEG 阳性组的 LOS 更长。sd 过滤后的 BSEEG 评分与谵妄筛查评分的相关性更强，死亡率预测更显着。

我们证实了 BSEEG 方法在检测谵妄和谵妄严重程度以及使用新的 EEG 设备预测患者预后方面的有用性。