A signal-off photoelectrochemical (PEC) aptasensor was proposed for pathogenic bacteria detection based on graphite-like carbon nitride decorated with NiO. The S. aureus be captured by the specific recognition of DNA aptamer, which was immobilized on the PEC electrode surface according to the specific effect of carboxylic group and NiO. The PEC signal would be obviously suppressed due to the transfer blocking of electron donor to PEC active material surface by steric hindrance and electrostatic repulsion. The PEC aptasensor showed excellent specificity and high sensitivity for S. aureus, and this provides simple strategy to construct point-of-care testing aptasensor for bacteria analysis.

中文翻译：

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基于氧化镍装饰的类石墨氮化碳的用于金黄色葡萄球菌检测的信号关闭光电化学适配体传感器

提出了一种基于 NiO 修饰的类石墨氮化碳的信号关闭光电化学 (PEC) 适体传感器用于病原菌检测。通过对DNA适配体的特异性识别捕获金黄色葡萄球菌，根据羧基和NiO的特异性作用将其固定在PEC电极表面。由于空间位阻和静电排斥将电子供体转移到PEC活性材料表面，PEC信号会明显受到抑制。PEC 适体传感器对金黄色葡萄球菌表现出优异的特异性和高灵敏度，这为构建用于细菌分析的即时检测适体传感器提供了简单的策略。