In the recent guideline statement from the American Society of Clinical Oncology, experts reviewed relevant literature and provided treatment recommendations for multimodality treatment approaches. The guidelines recommend either preoperative concurrent neoadjuvant chemoradiotherapy (CRT) or perioperative chemotherapy for locally advanced adenocarcinoma and either preoperative CRT followed by esophagectomy or definitive CRT for squamous cell carcinoma. Whether radiation can be omitted in patients with adenocarcinoma or whether surgery can be omitted in patients with squamous cell carcinoma is a subject of ongoing debate and clinical trials.

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局部晚期食管癌患者的三联疗法与双峰疗法：美国临床肿瘤学会实践指南评论

在美国临床肿瘤学会最近的指南声明中，专家们回顾了相关文献，并为多模式治疗方法提供了治疗建议。指南推荐局部晚期腺癌术前同步新辅助放化疗 (CRT) 或围手术期化疗，以及术前 CRT 后食管切除术或根治性 CRT 鳞状细胞癌。腺癌患者是否可以省略放疗或鳞状细胞癌患者是否可以省略手术是一个正在进行的辩论和临床试验的主题。