当前位置: X-MOL 学术Polym. Adv. Technol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Natural and synthetic functional materials for broad spectrum applications in antimicrobials, antivirals and cosmetics
Polymers for Advanced Technologies ( IF 3.4 ) Pub Date : 2021-07-31 , DOI: 10.1002/pat.5457
Dasharath B. Shinde 1 , Ranjitsinh Pawar 2 , Jyotsna Vitore 3, 4 , Deepak Kulkarni 5 , Shubham Musale 6 , Prabhanjan Giram 6
Affiliation  

Antimicrobial resistance is the leading cause of burden on healthcare sector. There is scientific challenge of developing new functional material as a platform to prevent and treat viral and microbial infection and cosmetic utility. In material chemistry, there is progress in the development of functional material with advent of nanotechnology with aid of synthetic organic chemistry. The properties and application of material can be changed significantly by modification of the surface functional groups (namely, COOH, HO, NH2OH, SO4,), formation of composite with inorganic material and incorporation of active pharmaceutical agents. In antibacterial application functional material of copper, silver, gold, platinum, tin, iron, cobalt, ruthenium, zinc and pharmaceutical antimicrobial agents found utility in the treatment of bacterial and hospital acquired infection with different resistant strains of microorganisms. In antiviral application many functional materials have been shown to possess remarkable antiviral ability like quantum dots, gold and silver nanoparticles, nanoclusters, carbon dots, graphene oxide and silicon materials. The polymers and dendrimers functionalized with USFDA approved antiviral agent also has potential therapeutic outcomes. Despite their difference in antiviral mechanism and inhibition efficacy, these functional material structures have unique features as potential antiviral candidates. In cosmetic applications functional material based on mica, sericite, fullerene, charcoal, peptides, mineral, lipids, glucocorticoid, nanocellulose hybrid material are extensively used. In this review, we have highlighted early promise and prospects of functional material for cosmetics, antibacterial and antiviral applications, advantages and disadvantages, Patent scenario, current challenges for translation into commercial products.

中文翻译:

用于抗菌剂、抗病毒剂和化妆品的广谱应用的天然和合成功能材料

抗菌素耐药性是医疗保健部门负担的主要原因。开发新的功能材料作为预防和治疗病毒和微生物感染以及美容用途的平台是一项科学挑战。在材料化学方面,随着纳米技术的出现,借助合成有机化学,功能材料的开发取得了进展。通过表面官能团(即COOH、HO、NH 2 OH、SO 4,),与无机材料形成复合物并掺入活性药物。在抗菌应用功能材料铜、银、金、铂、锡、铁、钴、钌、锌和药物抗菌剂中发现可用于治疗细菌和医院获得性感染的不同耐药菌株。在抗病毒应用中,许多功能材料已被证明具有显着的抗病毒能力,如量子点、金和银纳米粒子、纳米团簇、碳点、氧化石墨烯和硅材料。用美国食品药品监督管理局批准的抗病毒剂功能化的聚合物和树枝状聚合物也具有潜在的治疗效果。尽管它们在抗病毒机制和抑制功效上存在差异,这些功能材料结构作为潜在的抗病毒候选物具有独特的特性。在化妆品应用中,基于云母、绢云母、富勒烯、木炭、肽、矿物质、脂质、糖皮质激素、纳米纤维素混合材料的功能材料被广泛使用。在这篇综述中,我们重点介绍了化妆品功能材料的早期前景和前景、抗菌和抗病毒应用、优缺点、专利场景、转化为商业产品的当前挑战。
更新日期:2021-10-06
down
wechat
bug