Background Lower respiratory tract infections (LRTIs) are a leading cause of under-5 mortality in low-income and middle-income countries (LMICs) and interventions to reduce mortality are needed. Non-invasive ventilation has been shown to reduce mortality for neonates; however, data for children >1 month of age in LMICs are lacking. The objective of this study was to systematically review the available literature to determine if non-invasive ventilation as the primary modality of respiratory support is efficacious and safe for the management of respiratory distress in non-neonatal pediatric patients in LMICs.

中文翻译：

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低收入和中等收入国家儿科护理中无创通气的有效性和安全性：系统评价

背景下呼吸道感染 (LRTI) 是低收入和中等收入国家 (LMIC) 5 岁以下儿童死亡的主要原因，需要采取干预措施来降低死亡率。无创通气已被证明可以降低新生儿的死亡率；然而，缺乏中低收入国家 1 个月以上儿童的数据。本研究的目的是系统地回顾现有文献，以确定无创通气作为呼吸支持的主要方式对于管理中低收入国家非新生儿儿科患者的呼吸窘迫是否有效和安全。