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Activation of Aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithelial-mesenchymal transition via the MEK/ERK pathway
Helicobacter ( IF 4.4 ) Pub Date : 2021-07-30 , DOI: 10.1111/hel.12842
Nianshuang Li 1, 2 , Xinbo Xu 1 , Hui Yang 1 , Huan Wang 1 , Yaobin Ouyang 1 , Yanan Zhou 1 , Chao Peng 1 , Zhenxiang Yuan 1 , Cong He 1 , Chunyan Zeng 1 , Junbo Hong 1
Affiliation  

Helicobacter pylori (H. pylori) is a major risk factor for gastric cancer. The water channel protein Aquaporin 5 (AQP5) is involved in the tumorigenesis and progression of various cancers. In this study, we aimed to explore the role of AQP5 in H. pylori-induced gastric carcinogenesis.

中文翻译:

致癌性幽门螺杆菌感染激活水通道蛋白 5 通过 MEK/ERK 途径促进上皮间质转化

幽门螺杆菌( H. pylori ) 是胃癌的主要危险因素。水通道蛋白水通道蛋白 5 (AQP5) 参与各种癌症的肿瘤发生和进展。在本研究中,我们旨在探讨 AQP5 在幽门螺杆菌诱导的胃癌发生中的作用。
更新日期:2021-09-13
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