Electromagnetic radiation (EMR) in the environment has increased sharply in recent decades. The effect of environmental EMR on living organisms remains poorly characterized. Here, we report the impact of wireless-range EMR on the sleep architecture of mouse. Prolonged exposure to 2.4-GHz EMR modulated by 100-Hz square pulses at a nonthermal output level results in markedly increased time of wakefulness in mice. These mice display corresponding decreased time of nonrapid eye movement (NREM) and rapid eye movement (REM). In contrast, prolonged exposure to unmodulated 2.4-GHz EMR at the same time-averaged output level has little impact on mouse sleep. These observations identify alteration of sleep architecture in mice as a specific physiological response to prolonged wireless-range EMR exposure.

近几十年来，环境中的电磁辐射 (EMR) 急剧增加。环境 EMR 对生物体的影响仍然很差。在这里，我们报告了无线范围 EMR 对鼠标睡眠架构的影响。长时间暴露于由 100-Hz 方脉冲调制的 2.4-GHz EMR 在非热输出水平会导致小鼠清醒时间显着增加。这些小鼠显示非快速眼动 (NREM) 和快速眼动 (REM) 的时间相应减少。相比之下，在相同时间平均输出水平下长时间暴露于未调制的 2.4 GHz EMR 对鼠标睡眠几乎没有影响。这些观察结果将小鼠睡眠结构的改变确定为对长期无线范围 EMR 暴露的特定生理反应。