ABSTRACT

Introduction : Despite advances in diagnostic and therapeutic techniques breast cancer is still associated with significant morbidity and mortality. CTCs play a crucial role in the metastatic process, which is the main cause of death in BC patients.

Areas covered : This review discusses the prognostic and predictive value of CTCs and their prospective in management of BC patients.

Expert opinion : The analysis of CTCs through improved technologies offers a new insight into the metastatic cascade. Assessment of the number and molecular profile of CTCs holds great promises for disease monitoring and therapeutic decisions. However, more research is needed until they can be used in therapeutic decisions in clinical practice.

摘要

简介：尽管在诊断和治疗技术方面取得了进步，但乳腺癌仍然与显着的发病率和死亡率相关。CTCs 在转移过程中起着至关重要的作用，这是 BC 患者死亡的主要原因。

涵盖的领域：本综述讨论了 CTC 的预后和预测价值及其在 BC 患者管理中的前景。

专家意见：通过改进技术对 CTC 的分析提供了对转移级联的新见解。对 CTC 的数量和分子谱的评估为疾病监测和治疗决策提供了巨大的希望。然而，在它们可以用于临床实践中的治疗决策之前，还需要进行更多的研究。