Abstract

Two Co(II)-coordination polymers modified by a rigid amine 3,5-bis(imidazole-1-yl)pyridine (BIP), [Co₂(HPO₃)₂(BIP)]·H₂O (1) and [Co₃(HPO₃)₃(BIP)(H₂O)]·H₂O (2), were solvothermally prepared. Their improving effect on pre-eclampsia symptoms was evaluated and the related mechanism was explored at the same time. Firstly, the ELISA detection kits were performed to measure the levels of the Elabela in the plasma after indicated treatment. In addition to this, the urine protein content of pregnant mice after compound treatment was also determined with Braford protein content detection kit.

中文翻译：

---

通过增加 Elabela 改善 Co(II)-配位聚合物对先兆子痫症状的影响

摘要

由刚性胺 3,5-双(咪唑-1-基)吡啶 (BIP)、[Co ₂ (HPO ₃ ) ₂ (BIP)]·H ₂ O ( 1 ) 和[Co ₃ (HPO ₃ ) ₃ (BIP)(H ₂ O)]·H ₂ O ( 2)，溶剂热制备。评价其对子痫前期症状的改善作用，同时探讨相关机制。首先，使用ELISA检测试剂盒测量指定处理后血浆中Elabela的水平。除此之外，还用Braford蛋白含量检测试剂盒测定了复合处理后孕鼠的尿蛋白含量。