Kelch-like ECH-associated protein 1 (KEAP1) has been identified as a cancer driver gene in lung adenocarcinoma (LUAD), and increased evidence has given us clues about the association of KEAP1 mutation and immune characteristics. We assessed the association between KEAP1 mutation and tumor microenvironment in LUAD systematically.

中文翻译：

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KEAP1突变肺腺癌患者免疫细胞浸润低，免疫环境活性低

Kelch 样 ECH 相关蛋白 1 (KEAP1) 已被确定为肺腺癌 (LUAD) 中的癌症驱动基因，越来越多的证据为我们提供了有关 KEAP1 突变与免疫特征关联的线索。我们系统地评估了 LUAD 中 KEAP1 突变与肿瘤微环境之间的关联。